导言：

1，疼痛研究者太能灌水了！

2，各科的SCI论文困难户，都可以从疼痛研究中获得突破。

我们通过大数据分析，筛选出疼痛科最多的发表期刊、研究热点、最活跃的研究者；以及最关键的：极具借鉴价值的临床科研策略。

1，疼痛科论文概况

疼痛科领域已经发表了57,893篇Medline收录文献。

2011年，仅有1,972篇论文；到2020年目前，就已经达到9,055篇论文。十年翻4.6倍。

我们对其中最新发表的10,997篇论文进行大数据分析。

时间分布显示，全都是2019年及2020的文章。这也意味着，下面针对疼痛科研究的数据大都是今年最近1年论文分析结果。

国家分布可以看到，美国发表论文数最多，为4,928篇；中国发表的研究论文数量为888篇，占8.9%，排在第二位。加拿大、德国和意大利分列第三到五位。

研究发表在哪些杂志？

发表疼痛科相关研究最多的五个杂志是Anesth Analg, Pain, Pain Med, J Cardiothorac Vasc Anesth, J Clin Med等。

您在选刊投稿时可以从中选择期刊名中有Pain的期刊或者综合期刊。杂志后面附有影响因子，参考这个排名及影响因子，对于投稿有非常强的参考价值。

需要注意的是，IF=-1的标记意味着该期刊尽管被Medline数据库收录，但不是SCI收录期刊；尤其是其中的很多是掠夺性期刊，所以投稿时要特别小心。

研究热点基因和相关疾病

疼痛科研究的主要基因包括ITCH, APP, TRPV1, NAV1, SET等；神经痛、疼痛管理、睡眠、偏头痛和应激等是与疼痛科研究最关注的五种疾病。

疼痛研究最活跃的机构

最活跃的学者

疼痛科领域最活跃的学者及其关系网如下图所示。

很多同仁在找研究生导师、或者找访问学者导师，学术上活跃的学者总是最优先的选择。

包括：美国路易斯安那州立大学的Viswannath；德国Muenster大学医院的Zarbock, Alexander；美国华盛顿大学的Hay, Simon I；意大利La Maddalena癌症中心的Mercadante, Sebastiano；美国特种外科医院的Memtsoudis, Stavros G等。

2，中国发表的SCI论文

单独查中国疼痛科发表的论文时发现，中国已经发表了3,445篇Medline收录的论文，并且发文数量从2011年的29篇增长到2020年的821篇。

中国疼痛论文10年增长了28倍，显示了中国疼痛科临床科研的快速进步。

3，对临床科研的启发

大数据分析除了科研找到最喜欢疼痛研究的期刊之外，还可以找到临床科研做得最好的临床科研学者/医生，他们论文中展示的思路对于我们做临床科研有非常大的启发。

尤其是对于疼痛科的研究，我们可以看到，Omar教授在短短的1年左右时间里，竟然发表了99篇SCI论文；有兴趣的可以查他发文章的具体情况。并且，有十几位学者在这一年时间里，发表超过20篇SCI论文。强烈提示发表疼痛论文有套路。

所以，我们分享两位学者的研究思路。

1，英国Centre of Precision Rehabilitation for Spinal Pain (CPR Spine), School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham的Falla, Deborah。

在1年时间内，Deborah发表了21篇论文。并且都是不错的临床论文，所以分享给大家。

1. (2020) Influence of low back pain and its remission on motor abundance in a low-load lifting task Scientific reports
2. (2020) Measures of central sensitization and their measurement properties in musculoskeletal trauma: A systematic review European journal of pain (London, England)
3. (2020) Clinical predictive modelling of post-surgical recovery in individuals with cervical radiculopathy: a machine learning approach Scientific reports
4. (2020) Do measures of physical function enhance the prediction of persistent pain and disability following a whiplash injury? Protocol for a prospective observational study in Spain BMJ open
5. (2020) Eccentric exercise and delayed onset muscle soreness reduce the variability of active cervical movements Journal of biomechanics
6. (2020) Reliability of temporal summation, thermal and pressure pain thresholds in a healthy cohort and musculoskeletal trauma population PloS one
7. (2020) New insights into pain-related changes in muscle activation revealed by high-density surface electromyography Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology
8. (2020) Can People with Chronic Neck Pain Recognize Their Own Digital Pain Drawing? Pain physician
9. (2020) Divergent response of low- versus high-threshold motor units to experimental muscle pain The Journal of physiology
10. (2020) Interpretable machine learning models for classifying low back pain status using functional physiological variables European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
11. (2020) Probing the mechanisms underpinning recovery in post-surgical patients with cervical radiculopathy using Bayesian networks European journal of pain (London, England)
12. (2019) Are neuromuscular adaptations present in people with recurrent spinal pain during a period of remission? A protocol for a systematic review BMJ open
13. (2020) Variability of neck and trunk movement during single- and dual-task gait in people with chronic neck pain Clinical biomechanics (Bristol, Avon)
14. (2019) Are physical factors associated with poor prognosis following a whiplash trauma?: a protocol for a systematic review and data synthesis BMJ open
15. (2019) Predictors of pain reduction following manual therapy in patients with temporomandibular disorders: a protocol for a prospective observational study BMJ open
16. (2019) Can physical testing be used to distinguish between migraine and cervicogenic headache sufferers? A protocol for a systematic review BMJ open
17. (2019) High-Density Electromyography Provides New Insights into the Flexion Relaxation Phenomenon in Individuals with Low Back Pain Scientific reports
18. (2019) The effect of chronic, non-specific low back pain on superficial lumbar muscle activity: a protocol for a systematic review and meta-analysis BMJ open
19. (2020) The Extent of Pain Is Associated With Signs of Central Sensitization in Patients With Hip Osteoarthritis Pain practice : the official journal of World Institute of Pain
20. (2019) Rowers with a recent history of low back pain engage different regions of the lumbar erector spinae during rowing Journal of science and medicine in sport
21. (2019) Motor unit discharge rate and the estimated synaptic input to the vasti muscles is higher in open compared with closed kinetic chain exercise Journal of applied physiology (Bethesda, Md. : 1985)

总结这些研究，很多是前瞻性设计的预测模型或者预后不良指标研究。实际上，预测模型一直是临床医生最擅长的临床科研思路之一。如第2篇，颈神经根病患者手术后恢复的临床预测模型；第15篇，颞下颌关节疾病患者治疗后疼痛减轻的预测因素：一项前瞻性观察研究。

对于疼痛科医生，各类疼痛（治疗后）缓解的预测因素是很值得借鉴的研究思路。

2，韩国Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, Republic of Korea.||Department of Anesthesiology and Pain Medicine, Seoul National University College of Medicine的Lee, Ho-Jin。在1年左右发表了15篇SCI论文。

1. (2020) Effect of Fentanyl-Based Intravenous Patient-Controlled Analgesia with and without Basal Infusion on Postoperative Opioid Consumption and Opioid-Related Side Effects: A Retrospective Cohort Study Journal of pain research

2. (2020) Adjuvant chemotherapy as a risk factor for chronic postoperative pain after video-assisted thoracoscopic surgery: a 10-year single-centre retrospective study Interactive cardiovascular and thoracic surgery

3. (2020) Hydroxyethyl Starch 6% 130/0.4 in a Balanced Electrolyte Solution and Renal Function After Nephrectomy Anesthesia and analgesia

4. (2020) Validation and clinical utility of the Korean version of the Quality of Recovery-15 with enhanced recovery after surgery: a prospective observational cohort study British journal of anaesthesia

5. (2020) Medicolegal Consideration to Prevent Medical Malpractice Regarding Opioid Administration: An Analysis of Judicial Opinion in South Korea Journal of pain research

6. (2020) Long-term incidence of chronic postsurgical pain after thoracic surgery for lung cancer: a 10-year single-center retrospective study Regional anesthesia and pain medicine

7. (2020) Analysis of judicial precedent cases regarding epidural injection in chronic pain management in Republic of Korea Regional anesthesia and pain medicine

8. (2020) Pulsed Radiofrequency Ablation of the C2 Dorsal Root Ganglion Using a Posterior Approach for Treating Cervicogenic Headache: A Retrospective Chart Review Headache

9. (2020) Different Severity of Clinical Outcomes Between the 2 Subgroups of Stage 1 Acute Kidney Injury After Liver Transplantation Transplantation

10. (2020) Intensivist coverage and patient outcomes Journal of anesthesia

11. (2019) Epiduroscopic decompression of a symptomatic perineural cyst: A case report Medicine

12. (2019) Acute kidney injury and long-term renal function after partial nephrectomy-is there a true association? Annals of translational medicine

13. (2019) Complex regional pain syndrome in the young male population: a retrospective study of 200 Korean young male patients The Korean journal of pain

14. (2019) General Anesthetic Agents and Renal Function after Nephrectomy Journal of clinical medicine

15. (2019) Analysis of quantitative sudomotor axon reflex test patterns in patients with complex regional pain syndrome diagnosed using the Budapest criteria Regional anesthesia and pain medicine

Dr. Lee的研究思路更是极为清晰，就是针对疾病术后的回顾性研究，观察术后慢性疼痛发生的情况，第2、6、8和13篇论文，都是这个套路。

对于各科医生，都可以借鉴这个思路：

XXX疾病后慢性疼痛的发生情况：10年回顾性研究；

XXX术后慢性疼痛的发生情况：10年回顾性研究。

还有其他一些很有趣的研究，比如重点关注青少年慢性疼痛的研究，观察安慰剂疗效的研究，也都在1年内发了很多论文。

百度浏览   来源 : Hanson临床科研   

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